On November 24, 2025, President Trump signed an Executive Order, Launching the Genesis Mission, which establishes a national effort to use artificial intelligence to accelerate scientific discovery and strengthen U.S. capabilities in key technology domains.
Substantively, it places AI where nuclear technology sat during the Cold War: at the center of long-term strategic competition. The opening sections frame AI as a race for “global technology dominance” and liken the initiative to the Manhattan Project in urgency and ambition. The underlying purpose is to position the U.S. as strongly as possible to prevail in a decades-long technological “cold war” over AI capability:
The Genesis Mission charges the Secretary of Energy with leveraging our National Laboratories to unite America’s brightest minds, most powerful computers, and vast scientific data into one cooperative system for research (Genesis Mission Fact Sheet).
For business leaders, this is not just a science story. It is a signal about where the federal government is heading with AI – and how that direction will influence capital allocation, supply-chain expectations, and governance standards in critical sectors.
What the Genesis Mission Actually Does
The Executive Order establishes the Genesis Mission as a “national effort to accelerate the application of AI for transformative scientific discovery focused on pressing national challenges.” Instead of having AI initiatives scattered across federal agencies, it directs the government to build a shared AI . . . READ MORE
